DOSBox and Windows Vista and Windows 7
From DOSBoxWiki
Does it work ?
Yes, DOSBox works in both Vista 32 bit and Vista 64 bit, but depending on your local setup you might need to pay attention to certain things where can i download the 64 games
Configuration file
If you are running in Vista as non-administrator you must take care with editing the configuration file.
CD-ROM support
This is currently still in development. The best thing you can do is to make an image of your CD-ROM and IMGMOUNT that.
Note: I can mount my CDrom drive as "mount d e:\ -t cdrom" This is on a DELL Inspiron notebook