DOSBox and Windows Vista and Windows 7

Does it work ?

Yes, DOSBox works in both Vista 32 bit and Vista 64 bit. DOSBox also works on a Windows 7 environment 32bit and 64bit.

CD-ROM support

This is currently still in development. 95% of the functions work in 0.73, but if it doesn't work then the best thing you can do is to make an image of your CD-ROM and IMGMOUNT that.